Abstract: [Purpose/Significance] To provide references for improving China's participant and influence of international collaboration in the post-pandemic era, this paper explores the variation of the international collaboration patterns of China before and after the breaking out of COVID-19 . [Design/Methodology] Based on over 120 thousand scientific research papers in the bioRxiv platform, we create directed, weighted global co-authored relationship networks dominated by corresponding authors and analyze the international collaboration changes in China by measuring the increasing trend of collaboration numbers, the survival rate of collaboration relationship, the scale of collaboration partiners, the strength and the status in the collaboration. [Findings/Conclusion] Results indicate that after the global outbreak of COVID-19, the number, strength, and scale of international collaboration of China show a trend of first increase and then decrease, but international collaboration status of China has been an upward momentum,moreover, the collaboration status of China in the COVID-19 field is much higher than that in non-COVID-19 field. [Originality/Value] This study explores and measures the changes in the international scientific collaboration pattern and status of China before and after the pandemic, from the perspective of complex network,which helps to provide useful references for China to boost the influence of international collaboration.

Key words: Scientific collaboration, Complex network, Collaboration pattern, COVID-19, bioRxiv